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Applying single-molecule optical and AFM imaging and pressure-spectroscopy procedures, we seek out to unravel the mechanistic areas of the structure and dynamics of chromosomes. Our analysis passions include:

Our group experiments bacterial mobile division which is aiming to constitute a ‘base up biology’ in artificial cells that could autonomously divide. Our principal interest lies in mobile division, chromatin construction, and spatial Manage.

The following content are merged in Scholar. Their put together citations are counted just for the very first write-up.

Nanofabrication of electrodes with sub-five nm spacing for transport experiments on one molecules and metal clusters

De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt about het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft fulfilled veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de

Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en met 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en cees dekker moleculen te kunnen meten.

A lot of linked developments adopted, wherever our team recognized unique transistor variants which include one-electron transistors at home temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled various transistors into small evidence-of-basic principle Digital circuits.

2011, to start with in vitro measurements of transport throughout a single biomimetic nuclear pore complex; growth of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the mechanism of homology recognition in DNA homologous recombination

‘You should not just consider the queries of tomorrow, but in addition look at the inquiries of the working day after tomorrow’

‘The fantastically delicate way through which factors in nature function by no means ceases to amaze me. If we clear up the puzzle of how lifetime came into currently being, I assume that my amazement on the complexity of creation should have greater and with it my awe to the greatness in the Creator.’

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Later on we spoke all over again briefly because Dekker felt that our discussion of his faith quickly became purely philosophical, whereas Additionally, it concretely aids him in his operate.

Enable’s first look again for the time being whenever you decided to change your aim from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.

Supercoiling-dependent DNA binding: quantitative modeling and purposes to bulk and solitary-molecule experiments